A Stiff heart


Heart Failure With Preserved Ejection Fraction (HFpEF)

With preserved ejection fraction, the muscles in the heart chamber walls stiffen and thicken so the chamber cannot relax to fill with blood. This means the heart can’t pump out the blood the body needs.


Image of a normal heart muscle

Normal Heart

Strong muscular walls squeeze and relax to pump blood out to all the organs and other parts of the body.


Image of a stiff heart muscle

Heart Failure with preserved ejection fraction HFpEF

The heart muscle has become stiff and lost its ability to relax normally, so the heart can’t function as it should. About 50% of people with Heart Failure have HFpEF.


Most common symptoms

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Heart Icon

Shortness of breath with everyday activities

The heart can’t pump enough to keep up with the blood supply. This causes fluid to back up and leak into the lungs.

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Heart Icon

Shortness of breath with everyday activities

The heart can’t pump enough to keep up with the blood supply. This causes fluid to back up and leak into the lungs.


Leg Icon

Swelling in legs, feet, and ankles

Fluid backs up and collects in the tissues. The heart isn’t able to pump strongly enough to manage its workload.

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Leg Icon

Swelling in legs, feet, and ankles

Fluid backs up and collects in the tissues. The heart isn’t able to pump strongly enough to manage its workload.


Dry Cough Icon

A dry, hacking cough that doesn’t go away

The cough is caused by fluid backing up and leaking into the lungs. That’s because the heart can’t keep up with pumping the blood to the rest of the body.

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Dry Cough Icon

A dry, hacking cough that doesn’t go away

The cough is caused by fluid backing up and leaking into the lungs. That’s because the heart can’t keep up with pumping the blood to the rest of the body.


Trouble sleeping Icon

Trouble sleeping when you lie flat

Fluid backs up into the lungs because the heart can’t keep up with the blood supply.

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Trouble sleeping Icon

Trouble sleeping when you lie flat

Fluid backs up into the lungs because the heart can’t keep up with the blood supply.


Weight gain Icon

Rapid weight gain

The heart can’t keep up with the incoming blood supply, so fluid backs up and collects in the tissue.
(3 or more pounds in a day)

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Weight gain Icon

Rapid weight gain

The heart can’t keep up with the incoming blood supply, so fluid backs up and collects in the tissue.
(3 or more pounds in a day)


Tired Icon

Feeling tired

The limited blood supply is sent away from arm and leg muscles to supply the body’s main organs, like the heart and brain.

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Tired Icon

Feeling tired

The limited blood supply is sent away from arm and leg muscles to supply the body’s main organs, like the heart and brain.

Both types of Heart Failure share the same symptoms. Learn the differences.


Hear a real patient’s story

See how Cynthia discovered her HFpEF and what she does to stay on top of it.

Both types of Heart Failure share the same symptoms. Learn the differences.


Hear a real patient’s story

See how Cynthia discovered her HFpEF and what she does to stay on top of it.


Diagnosing Heart Icon

Diagnosing HFpEF

Diagnosing this kind of Heart Failure is more challenging because an ECG will show an ejection fraction in the normal range.

A process of elimination

When symptoms persist, doctors typically run a series of diagnostic tests. Eliminating other possibilities to arrive at a diagnosis of HFpEF can actually take up to a year and a half.

A process of elimination

When symptoms persist, doctors typically run a series of diagnostic tests. Eliminating other possibilities to arrive at a diagnosis of HFpEF can actually take up to a year and a half.


What it may take to diagnose:

Your doctor may suggest one or more of these tests to measure your ejection fraction:

  • Clinical signs of Heart Failure

  • Evidence of preserved or normal Left Ventricular Ejection Fraction (LVEF)

  • Evidence of abnormal Left Ventricular (LV) diastolic dysfunction that can be determined by Doppler echocardiography or cardiac catheterization

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